By measuring the level of glutathione in specific regions of the brain, Mandal says it is possible to diagnose Alzheimer's early.Lowering levels of this chemical in the hippocampus and frontal cortex regions of the brain is an indication of disease onset, Mandal has concluded based on studies done in healthy people as well as those suffering from Alzheimer's and MCI in different age groups.'In normal functioning of the brain, a lot of radicals are generated and glutathione absorbs them preventing any damage to brain cells.
'In Alzheimer's, neurons in left hippocampus are damaged while those in frontal cortex are damaged to a lesser extent.
By measuring glutathione levels in these two regions, we can decipher status of the disease,' explained Mandal.
'If someone comes to know that his or her glutathione level is low, the person can exercise, eat healthy food, increase intake of vitamins.
Such interventions can ensure that glutathione production cycle in the brain is not affected'.
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